{"id":144,"date":"2023-04-10T21:12:41","date_gmt":"2023-04-10T21:12:41","guid":{"rendered":"https:\/\/medicinal-cannabis.sv01.gmbdev.cloud\/?post_type=project&#038;p=144"},"modified":"2023-06-07T02:52:42","modified_gmt":"2023-06-07T02:52:42","slug":"prescribing","status":"publish","type":"project","link":"https:\/\/clinicalprimercannabis.com\/de\/module\/prescribing\/","title":{"rendered":"Prescribing"},"content":{"rendered":"\t\t<style>\r\n            #pdfp69f0fa8948d74 .title {  font-size: 16px; }#pdfp69f0fa8948d74 iframe {  height: 1122px; }#pdfp69f0fa8948d74 {  width: 100%; }                        .pdfpd8230efcbtn {background: #2271b1; color: #fff; padding: 10px 20px 10px 10px}        <\/style>\r\n                <div id=\"pdfp69f0fa8948d74\" class=\"pdfp_wrapper \" 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var(--gf-field-img-choice-check-ind-icon-size-md);--gf-field-pg-steps-number-color: rgba(17, 35, 55, 0.8);}<\/style><div id='gf_5' class='gform_anchor' tabindex='-1'><\/div>\n                        <div class='gform_heading'>\n                            <h2 class=\"gform_title\">Prescribing Quiz<\/h2>\n                            <p class='gform_description'><\/p>\n                        <\/div><form method='post' enctype='multipart\/form-data' target='gform_ajax_frame_5' id='gform_5' class='module-quiz-form' action='\/de\/wp-json\/wp\/v2\/project\/144#gf_5' data-formid='5' novalidate><div class='gf_invisible ginput_recaptchav3' data-sitekey='6Lf8FTAmAAAAADTeNlu6WYvKqZJhcIMMWPwngHZ3' data-tabindex='0'><input id=\"input_baf6c8a8d9651f63d56494042fa96ab9\" class=\"gfield_recaptcha_response\" type=\"hidden\" name=\"input_baf6c8a8d9651f63d56494042fa96ab9\" value=\"\"\/><\/div>\n        <div id='gf_progressbar_wrapper_5' class='gf_progressbar_wrapper' data-start-at-zero=''>\n        \t<p class=\"gf_progressbar_title\">Schritt <span class='gf_step_current_page'>1<\/span> von <span class='gf_step_page_count'>10<\/span><span class='gf_step_page_name'><\/span>\n        \t<\/p>\n            <div class='gf_progressbar gf_progressbar_custom' aria-hidden='true'>\n                <div class='gf_progressbar_percentage percentbar_custom percentbar_10' style='width:10%; color:#fff; background-color:#018a34;'><span>10%<\/span><\/div>\n            <\/div><\/div>\n                        <div class='gform-body gform_body'><div id='gform_page_5_1' class='gform_page ' data-js='page-field-id-0' >\n\t\t\t\t\t<div class='gform_page_fields'><div id='gform_fields_5' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_35\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Clinical Use<\/h2><\/div><fieldset id=\"field_5_5\" class=\"gfield gfield--type-checkbox gfield--type-choice gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label gfield_label_before_complex' >Name two (2) indications where cannabis-based medicines could be prescribed:<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_checkbox'><div class='gfield_checkbox ' id='input_5_5'><div class='gchoice gchoice_5_5_1'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_5.1' type='checkbox'  value='Cancer pain'  id='choice_5_5_1'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_5_1' id='label_5_5_1' class='gform-field-label gform-field-label--type-inline'>Cancer pain<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_5_2'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_5.2' type='checkbox'  value='Migraine headaches'  id='choice_5_5_2'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_5_2' id='label_5_5_2' class='gform-field-label gform-field-label--type-inline'>Migraine headaches<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_5_3'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_5.3' type='checkbox'  value='Major depressive disorder'  id='choice_5_5_3'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_5_3' id='label_5_5_3' class='gform-field-label gform-field-label--type-inline'>Major depressive disorder<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_5_4'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_5.4' type='checkbox'  value='Central neuropathic pain'  id='choice_5_5_4'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_5_4' id='label_5_5_4' class='gform-field-label gform-field-label--type-inline'>Central neuropathic pain<\/label>\n\t\t\t\t\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                         <input type='button' id='gform_next_button_5_7' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answers'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_2' class='gform_page' data-js='page-field-id-7' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_2' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_17\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>&#8220;Cancer pain&#8221; is a correct answer.<\/h2><\/div><div id=\"field_5_12\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>&#8220;Migraine Headaches&#8221; is an incorrect answer.<\/h2><\/div><div id=\"field_5_13\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>&#8220;Major depressive disorder&#8221; is an incorrect answer.<\/h2><\/div><div id=\"field_5_10\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>&#8220;Central neuropathic pain&#8221; is a correct answer.<\/h2><\/div><div id=\"field_5_33\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><p>Two indications where cannabis-based medicines could be prescribed are cancer pain and central neuropathic pain.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>\nCannabinoids have been used in a number of clinical settings and disease states. Indications include:\n<ul><li>Chronic pain, specifically neuropathic pain<\/li><li>Chemotherapy-induced nausea and vomiting; and anorexia associated with weight loss in patients with HIV\/AIDS<\/li>\n<li>Spasticity associated with multiple sclerosis<\/li>\n<li>Seizures associated with refractory epilepsy (Dravet syndrome or Lennox-Gastaut syndrome)\n<\/li><\/ul>\n<br\/>In particular, cannabinoids have been used in palliative care to enhance the quality of life of patients during the course of the illness (appetite stimulation, improving sleep, and relief of nausea), and to influence the affective qualities of pain\n<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_14' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_14' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_3' class='gform_page' data-js='page-field-id-14' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_3' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_4\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Dose Type<\/h2><\/div><fieldset id=\"field_5_36\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >Which route of administration can achieve a clinical effect within 5 \u2013 10 minutes?<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_5_36'>\n\t\t\t<div class='gchoice gchoice_5_36_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_36' type='radio' value='topical'  id='choice_5_36_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_36_0' id='label_5_36_0' class='gform-field-label gform-field-label--type-inline'>topical<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_5_36_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_36' type='radio' value='oral'  id='choice_5_36_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_36_1' id='label_5_36_1' class='gform-field-label gform-field-label--type-inline'>oral<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_5_36_2'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_36' type='radio' value='inhalation'  id='choice_5_36_2' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_36_2' id='label_5_36_2' class='gform-field-label gform-field-label--type-inline'>inhalation<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_5_36_3'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_36' type='radio' value='oromucosal'  id='choice_5_36_3' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_36_3' id='label_5_36_3' class='gform-field-label gform-field-label--type-inline'>oromucosal<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_16' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_16' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_4' class='gform_page' data-js='page-field-id-16' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_4' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_9\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>Inhalation is the correct answer.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>The pharmacokinetics of THC and CBD varies as a function of its route of administration. Administration via the pulmonary route can be a convenient, very rapid and efficient method of cannabinoid delivery, allowing self-titration to the desired therapeutic effect.<\/p><\/div><div id=\"field_5_37\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>Inhalation is the correct answer.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>The pharmacokinetics of THC and CBD varies as a function of its route of administration. Administration via the pulmonary route can be a convenient, very rapid and efficient method of cannabinoid delivery, allowing self-titration to the desired therapeutic effect.<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_24' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_24' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_5' class='gform_page' data-js='page-field-id-24' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_5' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_38\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Titration of Dose<\/h2><\/div><fieldset id=\"field_5_39\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >A titration period is required to reach a patients\u2019 personalised dose. What is a general rule when prescribing cannabis-based medicines?<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_5_39'>\n\t\t\t<div class='gchoice gchoice_5_39_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_39' type='radio' value='Start low, go with the flow and stay slow'  id='choice_5_39_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_39_0' id='label_5_39_0' class='gform-field-label gform-field-label--type-inline'>Start low, go with the flow and stay slow<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_5_39_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_39' type='radio' value='Start low, go slow and stay low'  id='choice_5_39_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_39_1' id='label_5_39_1' class='gform-field-label gform-field-label--type-inline'>Start low, go slow and stay low<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_5_39_2'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_39' type='radio' value='Start low, go rapidly and go high'  id='choice_5_39_2' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_39_2' id='label_5_39_2' class='gform-field-label gform-field-label--type-inline'>Start low, go rapidly and go high<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_5_39_3'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_39' type='radio' value='Start slow, go high and stay low'  id='choice_5_39_3' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_5_39_3' id='label_5_39_3' class='gform-field-label gform-field-label--type-inline'>Start slow, go high and stay low<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_22' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_22' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_6' class='gform_page' data-js='page-field-id-22' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_6' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_40\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>Start low, go slow and stay low is the correct answer.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>A titration period is required to reach a patients\u2019 personalised dose.<br\/>The correct dose of any cannabis-based medication is the lowest possible dose that achieves the desired clinical effect with a minimal side effect profile.<br\/><br\/>Depending upon the indication, it is suggested that during initial titration, doses are evenly spread out over the day and according to individual response and tolerability. Patients may gradually increase the dose until they achieve an optimal daily dosage.<br\/><br\/>A conservative dosing protocol should be used when managing frail and elderly patients, those with comorbidities, or those taking multiple medicines.<br\/>If medicine cessation is required, slow downward dose titration may be applicable.<\/p><\/div><div id=\"field_5_42\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>Start low, go slow and stay low is the correct answer.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>A titration period is required to reach a patients\u2019 personalised dose.<br\/>The correct dose of any cannabis-based medication is the lowest possible dose that achieves the desired clinical effect with a minimal side effect profile.<br\/><br\/>Depending upon the indication, it is suggested that during initial titration, doses are evenly spread out over the day and according to individual response and tolerability. Patients may gradually increase the dose until they achieve an optimal daily dosage.<br\/><br\/>A conservative dosing protocol should be used when managing frail and elderly patients, those with comorbidities, or those taking multiple medicines.<br\/>If medicine cessation is required, slow downward dose titration may be applicable.<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_28' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_28' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_7' class='gform_page' data-js='page-field-id-28' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_7' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_43\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Contraindications<\/h2><\/div><fieldset id=\"field_5_29\" class=\"gfield gfield--type-checkbox gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label gfield_label_before_complex' >There are some absolute and relative contraindications to cannabinoid use. Caution is advised when prescribing in the context of:<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_checkbox'><div class='gfield_checkbox ' id='input_5_29'><div class='gchoice gchoice_5_29_1'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_29.1' type='checkbox'  value='pregnancy,'  id='choice_5_29_1'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_29_1' id='label_5_29_1' class='gform-field-label gform-field-label--type-inline'>pregnancy,<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_29_2'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_29.2' type='checkbox'  value='psychiatric, substance dependence,'  id='choice_5_29_2'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_29_2' id='label_5_29_2' class='gform-field-label gform-field-label--type-inline'>psychiatric, substance dependence,<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_29_3'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_29.3' type='checkbox'  value='renal or hepatic disease, cardiovascular disease,'  id='choice_5_29_3'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_29_3' id='label_5_29_3' class='gform-field-label gform-field-label--type-inline'>renal or hepatic disease, cardiovascular disease,<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_29_4'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_29.4' type='checkbox'  value='the frail and elderly patients'  id='choice_5_29_4'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_29_4' id='label_5_29_4' class='gform-field-label gform-field-label--type-inline'>the frail and elderly patients<\/label>\n\t\t\t\t\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_30' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_30' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answers'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_8' class='gform_page' data-js='page-field-id-30' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_8' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_44\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>Cannabis-based medicines are contraindicated in the context of pregnancy, psychiatric, substance dependence, renal or hepatic disease, cardiovascular disease, and in frail and elderly patients.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>There is an incomplete understanding of the safety profile of cannabis-based medicines. Cannabinoids do have a number of important drug interactions which can result in altered pharmacokinetics or pharmacodynamics. With THC containing medicines, extra caution is advised in patients with a history of mental illness, cardiovascular disease, kidney and liver illness, the elderly and frail, and those with dementia. With high dose CBD medicines, caution is advised in patients with kidney and liver illness. Cannabinoids should be avoided in pregnancy and during lactation.<br\/>Refer to the Appendix for full tables: Clinical evaluation tools and Medicine Interactions.<\/p><\/div><div id=\"field_5_45\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>Cannabis-based medicines are contraindicated in the context of pregnancy, psychiatric, substance dependence, renal or hepatic disease, cardiovascular disease, and in frail and elderly patients.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>There is an incomplete understanding of the safety profile of cannabis-based medicines. Cannabinoids do have a number of important drug interactions which can result in altered pharmacokinetics or pharmacodynamics. With THC containing medicines, extra caution is advised in patients with a history of mental illness, cardiovascular disease, kidney and liver illness, the elderly and frail, and those with dementia. With high dose CBD medicines, caution is advised in patients with kidney and liver illness. Cannabinoids should be avoided in pregnancy and during lactation.<br\/>Refer to the Appendix for full tables: Clinical evaluation tools and Medicine Interactions.<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_46' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_46' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_9' class='gform_page' data-js='page-field-id-46' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_9' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_47\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Medicine Interactions<\/h2><\/div><fieldset id=\"field_5_48\" class=\"gfield gfield--type-checkbox gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label gfield_label_before_complex' >Which medications can interact with cannabis-based-medicines and can decrease the effect of THC and CBD?<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_checkbox'><div class='gfield_checkbox ' id='input_5_48'><div class='gchoice gchoice_5_48_1'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_48.1' type='checkbox'  value='Rifampicin'  id='choice_5_48_1'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_48_1' id='label_5_48_1' class='gform-field-label gform-field-label--type-inline'>Rifampicin<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_48_2'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_48.2' type='checkbox'  value='Dexamethason'  id='choice_5_48_2'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_48_2' id='label_5_48_2' class='gform-field-label gform-field-label--type-inline'>Dexamethason<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_48_3'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_48.3' type='checkbox'  value='Phenytoin'  id='choice_5_48_3'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_48_3' id='label_5_48_3' class='gform-field-label gform-field-label--type-inline'>Phenytoin<\/label>\n\t\t\t\t\t\t\t<\/div><div class='gchoice gchoice_5_48_4'>\n\t\t\t\t\t\t\t\t<input class='gfield-choice-input' name='input_48.4' type='checkbox'  value='Phenobarbital'  id='choice_5_48_4'   \/>\n\t\t\t\t\t\t\t\t<label for='choice_5_48_4' id='label_5_48_4' class='gform-field-label gform-field-label--type-inline'>Phenobarbital<\/label>\n\t\t\t\t\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_5_49' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_5_49' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answers'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_5_10' class='gform_page' data-js='page-field-id-49' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_5_10' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_5_50\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>Rifampicin, Dexamethason, Phenytoin, Phenobarbital<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>Review all medication use beforehand.<br\/><br\/>A number of commonly prescribed medicines interact with cannabis-based-medicines and can decrease the effect of THC and CBD and vice versa. Many patients will be co-prescribed with a number of other medicines metabolised by the liver\u2019s cytochrome P450 enzymes (CYP450). The potential for drug-drug interactions will increase when taken together with other medicines metabolised by the CYP450 system.<br\/><br\/>Refer to Appendix: Medicine Interactions for tables listing known and potential interactions.<\/p><\/div><div id=\"field_5_52\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>Rifampicin, Dexamethason, Phenytoin, Phenobarbital<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>Review all medication use beforehand.<br\/><br\/>A number of commonly prescribed medicines interact with cannabis-based-medicines and can decrease the effect of THC and CBD and vice versa. Many patients will be co-prescribed with a number of other medicines metabolised by the liver\u2019s cytochrome P450 enzymes (CYP450). The potential for drug-drug interactions will increase when taken together with other medicines metabolised by the CYP450 system.<br\/><br\/>Refer to Appendix: Medicine Interactions for tables listing known and potential interactions.<\/p><\/div><\/div><\/div>\n        <div class='gform-page-footer gform_page_footer top_label'><input type='submit' id='gform_previous_button_5' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='submit' id='gform_submit_button_5' class='gform_button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='submit' value='Submit'  \/> <input type='hidden' name='gform_ajax' value='form_id=5&amp;title=1&amp;description=1&amp;tabindex=0&amp;theme=orbital&amp;styles={&quot;theme&quot;:&quot;orbital&quot;,&quot;buttonPrimaryBackgroundColor&quot;:&quot;#018a34&quot;}&amp;hash=9076280361965f506dd6091e586d4441' \/>\n            <input type='hidden' class='gform_hidden' name='gform_submission_method' data-js='gform_submission_method_5' value='iframe' \/>\n            <input type='hidden' class='gform_hidden' name='gform_theme' data-js='gform_theme_5' id='gform_theme_5' value='orbital' \/>\n            <input type='hidden' class='gform_hidden' name='gform_style_settings' data-js='gform_style_settings_5' id='gform_style_settings_5' value='{&quot;theme&quot;:&quot;orbital&quot;,&quot;buttonPrimaryBackgroundColor&quot;:&quot;#018a34&quot;}' \/>\n            <input type='hidden' class='gform_hidden' name='is_submit_5' value='1' \/>\n            <input type='hidden' class='gform_hidden' name='gform_submit' value='5' \/>\n            \n            <input type='hidden' 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