{"id":162,"date":"2023-04-10T22:20:45","date_gmt":"2023-04-10T22:20:45","guid":{"rendered":"https:\/\/medicinal-cannabis.sv01.gmbdev.cloud\/?post_type=project&#038;p=162"},"modified":"2023-08-02T23:21:28","modified_gmt":"2023-08-02T23:21:28","slug":"pharmacology","status":"publish","type":"project","link":"https:\/\/clinicalprimercannabis.com\/de\/module\/pharmacology\/","title":{"rendered":"Pharmacology"},"content":{"rendered":"\t\t<style>\r\n            #pdfp69e5b4d69dfdb .title {  font-size: 16px; }#pdfp69e5b4d69dfdb iframe {  height: 1122px; }#pdfp69e5b4d69dfdb {  width: 100%; }                        .pdfp9ebca48cbtn {background: #2271b1; color: #fff; padding: 10px 20px 10px 10px}        <\/style>\r\n                <div id=\"pdfp69e5b4d69dfdb\" class=\"pdfp_wrapper \" 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var(--gf-field-img-choice-check-ind-icon-size-md);--gf-field-pg-steps-number-color: rgba(17, 35, 55, 0.8);}<\/style><div id='gf_8' class='gform_anchor' tabindex='-1'><\/div>\n                        <div class='gform_heading'>\n                            <h2 class=\"gform_title\">Pharmacology Quiz<\/h2>\n                            <p class='gform_description'><\/p>\n                        <\/div><form method='post' enctype='multipart\/form-data' target='gform_ajax_frame_8' id='gform_8' class='module-quiz-form' action='\/de\/wp-json\/wp\/v2\/project\/162#gf_8' data-formid='8' novalidate><div class='gf_invisible ginput_recaptchav3' data-sitekey='6Lf8FTAmAAAAADTeNlu6WYvKqZJhcIMMWPwngHZ3' data-tabindex='0'><input id=\"input_0180b06e4c723e1869a668485293411f\" class=\"gfield_recaptcha_response\" type=\"hidden\" name=\"input_0180b06e4c723e1869a668485293411f\" value=\"\"\/><\/div>\n        <div id='gf_progressbar_wrapper_8' class='gf_progressbar_wrapper' data-start-at-zero=''>\n        \t<p class=\"gf_progressbar_title\">Schritt <span class='gf_step_current_page'>1<\/span> von <span class='gf_step_page_count'>12<\/span><span class='gf_step_page_name'><\/span>\n        \t<\/p>\n            <div class='gf_progressbar gf_progressbar_custom' aria-hidden='true'>\n                <div class='gf_progressbar_percentage percentbar_custom percentbar_8' style='width:8%; color:#fff; background-color:#018a34;'><span>8%<\/span><\/div>\n            <\/div><\/div>\n                        <div class='gform-body gform_body'><div id='gform_page_8_1' class='gform_page ' data-js='page-field-id-0' >\n\t\t\t\t\t<div class='gform_page_fields'><div id='gform_fields_8' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_4\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Cannabinoids<\/h2><\/div><fieldset id=\"field_8_33\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >Cannabinoids are:<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_8_33'>\n\t\t\t<div class='gchoice gchoice_8_33_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_33' type='radio' value='drug substances which act on the cannabinoid receptors (CB1 and CB2).'  id='choice_8_33_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_33_0' id='label_8_33_0' class='gform-field-label gform-field-label--type-inline'>drug substances which act on the cannabinoid receptors (CB1 and CB2).<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_33_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_33' type='radio' value='cannabis plants, plant material or whole plant extracts used for medical reasons.'  id='choice_8_33_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_33_1' id='label_8_33_1' class='gform-field-label gform-field-label--type-inline'>cannabis plants, plant material or whole plant extracts used for medical reasons.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_33_2'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_33' type='radio' value='endogenous, plant-derived and synthetic agents with pharmacological activity at the G-protein coupled cannabinoid receptors (CB1 and CB2).'  id='choice_8_33_2' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_33_2' id='label_8_33_2' class='gform-field-label gform-field-label--type-inline'>endogenous, plant-derived and synthetic agents with pharmacological activity at the G-protein coupled cannabinoid receptors (CB1 and CB2).<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_33_3'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_33' type='radio' value='cannabinoid receptors (CB1 and CB2).'  id='choice_8_33_3' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_33_3' id='label_8_33_3' class='gform-field-label gform-field-label--type-inline'>cannabinoid receptors (CB1 and CB2).<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                         <input type='button' id='gform_next_button_8_7' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_2' class='gform_page' data-js='page-field-id-7' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_2' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_17\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>Cannabinoids are endogenous, plant-derived and synthetic agents with pharmacological activity at the G-protein coupled cannabinoid receptors (CB1 and CB2).<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>Plant-derived cannabinoids are termed phytocannabinoids.<br\/><br\/>The phytocannabinoids are pre-cursor substances synthesised by the Cannabis sativa L. plant, including tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA). Heating to temperatures above 100\u00baC causes decarboxylation (releasing CO2), converting the acids into their bioactive forms, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC and CBD interact with cannabinoid receptors (CB) within the human endocannabinoid system (ECS).<\/p><\/div><div id=\"field_8_34\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>Cannabinoids are endogenous, plant-derived and synthetic agents with pharmacological activity at the G-protein coupled cannabinoid receptors (CB1 and CB2).<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>Plant-derived cannabinoids are termed phytocannabinoids.<br\/><br\/>The phytocannabinoids are pre-cursor substances synthesised by the Cannabis sativa L. plant, including tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA). Heating to temperatures above 100\u00baC causes decarboxylation (releasing CO2), converting the acids into their bioactive forms, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC and CBD interact with cannabinoid receptors (CB) within the human endocannabinoid system (ECS).<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_35' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_35' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_3' class='gform_page' data-js='page-field-id-35' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_3' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_36\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Endocannabinoid System<\/h2><\/div><fieldset id=\"field_8_37\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >The human endocannabinoid system (ECS):<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_8_37'>\n\t\t\t<div class='gchoice gchoice_8_37_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_37' type='radio' value='consists of cannabinoid receptors (CB)'  id='choice_8_37_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_37_0' id='label_8_37_0' class='gform-field-label gform-field-label--type-inline'>consists of cannabinoid receptors (CB)<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_37_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_37' type='radio' value='consists of cannabinoid receptors (CB) which are activated by naturally produced endocannabinoids'  id='choice_8_37_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_37_1' id='label_8_37_1' class='gform-field-label gform-field-label--type-inline'>consists of cannabinoid receptors (CB) which are activated by naturally produced endocannabinoids<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_37_2'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_37' type='radio' value='consists of N-arachidonoylethanolamine (anandamide; AEA) and 2-arachidonylglycerol (2-AG)'  id='choice_8_37_2' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_37_2' id='label_8_37_2' class='gform-field-label gform-field-label--type-inline'>consists of N-arachidonoylethanolamine (anandamide; AEA) and 2-arachidonylglycerol (2-AG)<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_37_3'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_37' type='radio' value='contains cannabinoid receptors (CB) and is involved in a host of homeostatic and physiologic functions.'  id='choice_8_37_3' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_37_3' id='label_8_37_3' class='gform-field-label gform-field-label--type-inline'>contains cannabinoid receptors (CB) and is involved in a host of homeostatic and physiologic functions.<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_38' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_38' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_4' class='gform_page' data-js='page-field-id-38' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_4' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_39\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>The ECS contains cannabinoid receptors and is involved in a host of homeostatic and physiologic functions.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>The human endocannabinoid system (ECS) contains cannabinoid receptors (CB) which are activated by naturally produced endocannabinoids.<br\/><br\/>The ECS plays a critical role in the nervous system and regulates multiple physiological processes, including the adjustment of the response to pain, appetite, digestion, sleep, mood, and memory.<br\/><br\/>The ECS also influences seizure thresholds, coordination, sensory integration (touch, balance, sense of space), and other processes such as the immune system and inflammation, heart function, fertility, bone physiology, the central stress response system, neural development, and eye pressure.<\/p><\/div><div id=\"field_8_40\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>The ECS contains cannabinoid receptors and is involved in a host of homeostatic and physiologic functions.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>The human endocannabinoid system (ECS) contains cannabinoid receptors (CB) which are activated by naturally produced endocannabinoids.<br\/><br\/>The ECS plays a critical role in the nervous system and regulates multiple physiological processes, including the adjustment of the response to pain, appetite, digestion, sleep, mood, and memory.<br\/><br\/>The ECS also influences seizure thresholds, coordination, sensory integration (touch, balance, sense of space), and other processes such as the immune system and inflammation, heart function, fertility, bone physiology, the central stress response system, neural development, and eye pressure.<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_47' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_47' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_5' class='gform_page' data-js='page-field-id-47' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_5' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_48\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Cannabinoid Receptors<\/h2><\/div><fieldset id=\"field_8_43\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >Two types of cannabinoid receptors &#8211; CB1 and CB2 &#8211; have been identified with certainty. The CB1 receptors widely expressed in:<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_8_43'>\n\t\t\t<div class='gchoice gchoice_8_43_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_43' type='radio' value='peripheral organs and tissues controlling immune responses and inflammatory reactions'  id='choice_8_43_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_43_0' id='label_8_43_0' class='gform-field-label gform-field-label--type-inline'>peripheral organs and tissues controlling immune responses and inflammatory reactions<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_43_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_43' type='radio' value='areas of the brain controlling pain, appetite, emotion and nausea'  id='choice_8_43_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_43_1' id='label_8_43_1' class='gform-field-label gform-field-label--type-inline'>areas of the brain controlling pain, appetite, emotion and nausea<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_44' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_44' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_6' class='gform_page' data-js='page-field-id-44' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_6' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_45\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>The CB1 receptors are widely expressed in areas of the brain controlling pain, appetite, emotion and nausea.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>Cannabinoid receptors (CB) belong to the superfamily of the G-protein-coupled receptors that mediate the pharmacological effects of phyto-cannabinoids, endocannabinoids, and synthetic cannabimimetic compounds.<br\/><br\/>The CB1 isoform is highly expressed in the central nervous system. It is thought to be the most widely expressed G-protein coupled receptor in the brain. Indeed, the CB1 receptors are concentrated in areas controlling pain, appetite, emotion and nausea, corresponding to the most prominent behavioural effects. CB1 receptors mediate most, if not all, of the psychoactive effects of THC and related compounds.<\/p><\/div><div id=\"field_8_46\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>The CB1 receptors are widely expressed in areas of the brain controlling pain, appetite, emotion and nausea.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>Cannabinoid receptors (CB) belong to the superfamily of the G-protein-coupled receptors that mediate the pharmacological effects of phyto-cannabinoids, endocannabinoids, and synthetic cannabimimetic compounds.<br\/><br\/>The CB1 isoform is highly expressed in the central nervous system. It is thought to be the most widely expressed G-protein coupled receptor in the brain. Indeed, the CB1 receptors are concentrated in areas controlling pain, appetite, emotion and nausea, corresponding to the most prominent behavioural effects. CB1 receptors mediate most, if not all, of the psychoactive effects of THC and related compounds.<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_41' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_41' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_7' class='gform_page' data-js='page-field-id-41' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_7' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_54\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>THC<\/h2><\/div><fieldset id=\"field_8_55\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >delta-9-tetrahydrocannabinol (THC) activates both CB1 and CB2 receptors. THC is:<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_8_55'>\n\t\t\t<div class='gchoice gchoice_8_55_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_55' type='radio' value='psychoactive.'  id='choice_8_55_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_55_0' id='label_8_55_0' class='gform-field-label gform-field-label--type-inline'>psychoactive.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_55_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_55' type='radio' value='euphorigenic at high doses.'  id='choice_8_55_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_55_1' id='label_8_55_1' class='gform-field-label gform-field-label--type-inline'>euphorigenic at high doses.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_55_2'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_55' type='radio' value='psychoactive, is euphorigenic, and has intoxicating effects at high doses.'  id='choice_8_55_2' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_55_2' id='label_8_55_2' class='gform-field-label gform-field-label--type-inline'>psychoactive, is euphorigenic, and has intoxicating effects at high doses.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_55_3'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_55' type='radio' value='psychoactive but does not have intoxicating effects.'  id='choice_8_55_3' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_55_3' id='label_8_55_3' class='gform-field-label gform-field-label--type-inline'>psychoactive but does not have intoxicating effects.<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_50' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_50' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_8' class='gform_page' data-js='page-field-id-50' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_8' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_51\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>THC is psychoactive, is euphorigenic, and has intoxicating* effects at high doses.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>THC is psychoactive, is euphorigenic, and has intoxicating* effects at high doses. Synthetic and semi-synthetic cannabinoids mimic the effects of THC. In the body, THC is converted to a potent psychoactive metabolite, 11-hydroxy-THC (11-OHTHC). THC activates both CB1 and CB2 receptors (as a partial agonist with high affinity), which in turn influences the activity of various physiological systems.<\/p>\n<\/br>\n<p><em>* WHO. ICD-10: Intoxication is a transient condition that follows the administration of a psychoactive substance and results in disturbances in the level of consciousness, cognition, perception, judgement, or behaviour, or other psycho-physiological functions and responses.<\/em><\/p><\/div><div id=\"field_8_52\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>THC is psychoactive, is euphorigenic, and has intoxicating effects at high doses.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>THC is psychoactive, is euphorigenic, and has intoxicating* effects at high doses. Synthetic and semi-synthetic cannabinoids mimic the effects of THC. In the body, THC is converted to a potent psychoactive metabolite, 11-hydroxy-THC (11-OHTHC). THC activates both CB1 and CB2 receptors (as a partial agonist with high affinity), which in turn influences the activity of various physiological systems.<\/p>\n<\/br>\n<p><em>* WHO. ICD-10: Intoxication is a transient condition that follows the administration of a psychoactive substance and results in disturbances in the level of consciousness, cognition, perception, judgement, or behaviour, or other psycho-physiological functions and responses.<\/em><\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_59' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_59' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_9' class='gform_page' data-js='page-field-id-59' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_9' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_60\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>CBD<\/h2><\/div><fieldset id=\"field_8_49\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >Cannabidiol(CBD) is a partial antagonist of the CB1 and CB2 receptors. CBD is:<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_8_49'>\n\t\t\t<div class='gchoice gchoice_8_49_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_49' type='radio' value='psychoactive, is euphorigenic, and has intoxicating effects at high doses.'  id='choice_8_49_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_49_0' id='label_8_49_0' class='gform-field-label gform-field-label--type-inline'>psychoactive, is euphorigenic, and has intoxicating effects at high doses.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_49_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_49' type='radio' value='is psychoactive but does not have intoxicating effects.'  id='choice_8_49_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_49_1' id='label_8_49_1' class='gform-field-label gform-field-label--type-inline'>is psychoactive but does not have intoxicating effects.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_49_2'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_49' type='radio' value='is euphorigenic, and has intoxicating effects at high doses.'  id='choice_8_49_2' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_49_2' id='label_8_49_2' class='gform-field-label gform-field-label--type-inline'>is euphorigenic, and has intoxicating effects at high doses.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_49_3'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_49' type='radio' value='is psychoactive.'  id='choice_8_49_3' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_49_3' id='label_8_49_3' class='gform-field-label gform-field-label--type-inline'>is psychoactive.<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_56' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_56' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_10' class='gform_page' data-js='page-field-id-56' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_10' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_57\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>CBD is psychoactive but does not have intoxicating effects.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>CBD, by comparison to THC, has less affinity for the CB1 and CB2 receptors and works to partly block receptor activity (as a partial antagonist).<\/p><\/div><div id=\"field_8_58\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>CBD is psychoactive but does not have intoxicating effects.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>CBD, by comparison to THC, has less affinity for the CB1 and CB2 receptors and works to partly block receptor activity (as a partial antagonist).<\/p><\/div><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_53' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_53' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Continue'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_11' class='gform_page' data-js='page-field-id-53' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_11' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_42\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Route of Administration<\/h2><\/div><fieldset id=\"field_8_61\" class=\"gfield gfield--type-radio gfield--type-choice gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><legend class='gfield_label gform-field-label' >What are the two major administration routes?:<span class=\"gfield_required\"><span class=\"gfield_required gfield_required_text\">(erforderlich)<\/span><\/span><\/legend><div class='ginput_container ginput_container_radio'><div class='gfield_radio' id='input_8_61'>\n\t\t\t<div class='gchoice gchoice_8_61_0'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_61' type='radio' value='inhalation and oral.'  id='choice_8_61_0' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_61_0' id='label_8_61_0' class='gform-field-label gform-field-label--type-inline'>inhalation and oral.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_61_1'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_61' type='radio' value='oromucosal and inhalation.'  id='choice_8_61_1' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_61_1' id='label_8_61_1' class='gform-field-label gform-field-label--type-inline'>oromucosal and inhalation.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_61_2'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_61' type='radio' value='topical and oral.'  id='choice_8_61_2' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_61_2' id='label_8_61_2' class='gform-field-label gform-field-label--type-inline'>topical and oral.<\/label>\n\t\t\t<\/div>\n\t\t\t<div class='gchoice gchoice_8_61_3'>\n\t\t\t\t\t<input class='gfield-choice-input' name='input_61' type='radio' value='inhalation and rectal.'  id='choice_8_61_3' onchange='gformToggleRadioOther( this )'    \/>\n\t\t\t\t\t<label for='choice_8_61_3' id='label_8_61_3' class='gform-field-label gform-field-label--type-inline'>inhalation and rectal.<\/label>\n\t\t\t<\/div><\/div><\/div><\/fieldset><\/div>\n                    <\/div>\n                    <div class='gform-page-footer gform_page_footer top_label'>\n                        <input type='button' id='gform_previous_button_8_62' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='button' id='gform_next_button_8_62' class='gform_next_button gform-theme-button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='next' value='Submit Answer'  \/> \n                    <\/div>\n                <\/div>\n                <div id='gform_page_8_12' class='gform_page' data-js='page-field-id-62' style='display:none;'>\n                    <div class='gform_page_fields'>\n                        <div id='gform_fields_8_12' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id=\"field_8_63\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Correct<\/h2>\n<p>The two major administration routes are oromucosal and inhalation.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>The pharmacokinetics of THC and CBD varies as a function of its route of administration. The management of the dose is critical to balance the desired therapeutic effects against the prevention of side effects.<br\/><br\/>There are two major administration routes:<ul><li>By inhalation \u2013 pulmonary absorption, and<\/li><li>By mouth \u2013 oromucosal solutions, sprays and wafers with sublingual or buccal absorption, or ingested oral solutions and capsules with small intestine absorption.<\/li><\/ul><\/p><\/div><div id=\"field_8_64\" class=\"gfield gfield--type-html gfield--width-full gfield_html gfield_html_formatted gfield_no_follows_desc field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible\"  ><h2>Incorrect<\/h2>\n<p>The two major administration routes are oromucosal and inhalation.<\/p>\n<br\/>\n<h3>Reasoning<\/h3>\n<p>The pharmacokinetics of THC and CBD varies as a function of its route of administration. The management of the dose is critical to balance the desired therapeutic effects against the prevention of side effects.<br\/><br\/>There are two major administration routes:<ul><li>By inhalation \u2013 pulmonary absorption, and<\/li><li>By mouth \u2013 oromucosal solutions, sprays and wafers with sublingual or buccal absorption, or ingested oral solutions and capsules with small intestine absorption.<\/li><\/ul><\/p><\/div><\/div><\/div>\n        <div class='gform-page-footer gform_page_footer top_label'><input type='submit' id='gform_previous_button_8' class='gform_previous_button gform-theme-button gform-theme-button--secondary button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='previous' value='Previous'  \/> <input type='submit' id='gform_submit_button_8' class='gform_button button' onclick='gform.submission.handleButtonClick(this);' data-submission-type='submit' value='Submit'  \/> <input type='hidden' name='gform_ajax' 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